The Neuroimage Project covers several aspects of managing and assessing images in clinical trials, observer reliability studies and teaching about imaging. SIRS is the function for rating scans in clinical trials and observer reliability studies (further details see SIRS Information).
SIRS is ideal for studies where a series of axial images or other static images are to be reviewed. It does not currently handle video images or enable detailed measurements (although the latter is under development). It has only been used in radiological images (CT and MR) so far but could be used for other types of images such as photographs of skin lesions or histological sections, although the image quality has been not been tested for these purposes as yet.
SIRS is currently being used in the following studies:
- For central scan management and reading in IST-3
- In a multi-reader study of observer reliability of MR signs in sporadic CJD
- In a National Registry of Intracranial Vascular Malformations